Juan R. Del Valle * Associate Professor * Department of Chemistry * University of South Florida 4202 East Fowler Ave. * NES 331 * Tampa, FL 33620 * ph: (813) 974-7306 * email: firstname.lastname@example.org
B-I09 inhibition of ER stress response and RIDD March 21, 2018
Check out 3 new papers in collaboration with the Hu, Xu, and Simon labs showing the efficacy of B-I09 for shutting down IRE1-mediated ER stress response! B-I09 blocks the onset of graft-versus-host disease and confers synthetic lethality in Myc-driven cancers in vivo.
Khalilia advances to candidacy March 9, 2018
Congratulations to 2nd year graduate student Khalilia Tillett, who advanced to Ph.D. candidacy!
Ben advances to candidacy February 17, 2018
Congratulations to Ben Rathman, 2nd year grad student, who advanced to Ph.D. candidacy!
Covalently restricted N-amino peptides August 18, 2017
Our paper on the beta-sheet propensity of various constrained N-amino peptides was accepted in Bioorganic and Medicinal Chemistry. Good job Matt and Kyle!
Grant news August 1, 2017
The lab received a 3-year grant from the National Science foundation to develop novel protein mimics based on N-heteroatom-substituted peptides.
New undergrad researchers! June 1, 2017
The lab welcomes Evan B., Megan, and Evan H. -- 3 undergraduate researchers that joined the lab in summer 2017!
Yassin wins travel award! May 2, 2017
Congratulations to Yassin Elbatrawi, who was the recipient of a 2017 Martin travel award to attend this year's American Peptide Society Symposium in Whistler, Canada!
ER stress response modulates dendritic cell survival May 1, 2017
Our collaborative paper with the Janssens and Hu labs appeared as an Advance Online manuscript in Nature Cell Biology.
Matt wins APS travel award... April 15, 2017
Congratulations to Matt Sarnowski, who was the recipient of a 2017 APS travel award to attend this year's American Peptide Society Symposium in Whistler, Canada!
Hot off the press... January 20, 2017
Matt's ACIE paper is now online (Early View) and has been selected as a 'Hot Paper' by the journal's editorial staff!
N-amino peptides... "How-to" January 13, 2017
Our paper on hydrazino acid and N-amino peptide synthesis was accepted in the Journal of Organic Chemistry. Way to go Changwon, Matt, and Yassin!
Beta-sheets stabilized by backbone amination January 11, 2017 Congratulations to Matt, Changwon, and Yassin on their recent Angewandte Chemie paper on the conformational effects of a new peptide backbone modification!
Chris advances to candidacy December 7, 2016
Congratulations to Chris Cain, 2nd year grad student, who advanced to Ph.D. candidacy!
Matt advances to candidacy December 6, 2016
Congratulations to Matt Sarnowski who advanced to Ph.D. candidacy!
New grad student October 26, 2016
Welcome to new graduate student, Ben Rathman from the University of North Florida.
New grad student October 24, 2016
The lab welcomes new graduate student Khalilia Tillet from Murray State University.
New grad student October 18, 2016
Welcome to new graduate student Kyle Pedretty, from the College of the Holy Cross.
Farewell Bomi August 5, 2016
Goodbye to Bomi, our skilled 'oxaziridinator', who returns to South Korea after a 5-month internship in the lab. Best of luck!
Yassin advanced to candidacy April 27, 2016
Congratulations to Yassin Elbatrawi, who advanced to Ph.D. candidacy!
New grad student April 6, 2016
The lab welcomes new graduate student Chris Cain, from Auburn Univeristy.
1st Place poster April 4, 2016
Congratulations to Matt for winning 1st place at the 14th Raymond Castle Student Research Conference for his poster entitled "Synthesis and conformational analysis of N-amino peptides"!
STING-ing cancer... March 5, 2016
Our paper in collaboration with the Hu lab (Wistar Institute) on STING-mediated cancer cell apoptosis was published in Cancer Research!
New postdoctoral researcher January 11, 2016 Welcome to Dr. Justin Goodwin, our new postdoctoral researcher. Justin comes to us from the Aponick lab at the University of Florida.
New grad student January 11, 2016
The lab welcomes its newest graduate student, Bill Motsch, from McGill University.
Beta-strands in stitches... September 10, 2015
Our paper on tpd-based stitched beta-strand mimics was accepted in Chemical Communications. Congratulations to ChangWon and Matt!
Grant news September 7, 2015
The lab received an NIH R01 grant to study novel inhibitors of XBP-1s expression as antileukemic agents.
Heterocyclic beta-strand stabilizers September 2, 2015
Our review on heterocyclic extended dipeptide surrogates is now in press. See the Publications page for details.
Grant news September 01, 2015
The lab was awarded a 2-year grant from the NIH in support of a medicinal chemistry campaign toward antagonists of IRE-1 RNase activity.
Moving day! August 21, 2015
We've completed our move to the Department of Chemistry at USF. Our new lab and website are up and running. We look forward to an exciting new chapter...